(Photo credit: Mitch Stringer-Imagn Images)

Royce Lewis hit a two-run home run and the Minnesota Twins won for the first time under first-year manager Derek Shelton by beating the host Baltimore Orioles 4-1 on Saturday.

Six Minnesota pitchers combined on a five-hitter while striking out 16 batters and walking six.

The Twins prevailed despite managing only four hits - including two by Byron Buxton - with the bats. The outcome came in the second game of the season-opening series.

Anthony Banda (1-0) was the winning pitcher with two-thirds of an inning of relief. Cole Sands worked the ninth and was credited with a save.

The Orioles stranded 11 runners on base. Jeremiah Jackson had two hits for Baltimore.

Minnesota starter Taj Bradley struck out nine in 4 1/3 innings, allowing one run on three hits but he was finished after 92 pitches.

Orioles starter Kyle Bradish (0-1) was done after 4 2/3 innings, allowing three runs (two earned) on two hits and taking the loss. He walked three and struck out four.

Baltimore scored first on Jackson's run-scoring single.

Josh Bell's sacrifice fly tied it in the fourth. When Lewis belted his homer in the fifth, it gave the Twins a lead for the first time this season.

Lewis had 13 home runs last year while playing a career-high 106 games.

Banda entered behind Bradley and notched strikeouts for his two outs and then Kody Funderburk fanned the first two Orioles in the sixth, so it meant that 13 of the first 17 outs recorded by the Twins came via strikeouts.

The Orioles loaded the bases with two outs in the sixth. Eric Orze got Gunnar Henderson on a flyout to end the threat.

The Twins tacked on a run in the seventh on Kody Clemens' two-out single that drove in Lewis.

Baltimore used five pitchers, registering a total of 10 strikeouts.

The result handed Baltimore's Craig Albernaz his first loss as a big-league manager.

--Field Level Media