(Photo credit: Stan Szeto-Imagn Images)

Shohei Ohtani pitched six shutout innings, but Patrick Bailey belted a tiebreaking three-run homer off reliever Jack Dreyer in the seventh, lifting the San Francisco Giants to a 3-0 victory over the visiting Los Angeles Dodgers on Wednesday.

Tyler Mahle (1-3) tossed seven innings and teamed with two relievers on a four-hitter, giving the Giants a second straight low-scoring win over the two-time defending champs. San Francisco prevailed 3-1 in the series opener on Tuesday.

Ohtani and Mahle matched zeros for six innings before the Dodgers star was pulled after having thrown 91 pitches. He has pitched exactly six innings in his four starts this season, and he owns a National League-leading 0.38 ERA.

Ohtani limited the Giants to five hits and struck out seven without walking a batter.

The Giants jumped on Dreyer (1-1) in the bottom of the seventh.

Jung Hoo Lee and Heliot Ramos began the frame with consecutive singles, and each advanced a base on Drew Gilbert's sacrifice bunt.

The left-handed Dreyer then got two strikes on Bailey, the No. 9 batter, before the switch hitter launched his first homer of the season into the bleachers in left field.

The RBIs were just the second, third and fourth of the season for Bailey, the Giants' regular catcher.

San Francisco's Caleb Kilian survived a leadoff single by Miguel Rojas to throw a scoreless eighth. Ryan Walker worked a hitless ninth for his third save of the season, his second in two nights.

Mahle, who entered the game with a 7.23 ERA, allowed three hits and two walks while striking out five.

Ohtani went 0-for-4 at the plate, snapping his streak of 53 straight games of having reached base safely. The run, which dated back to last season, equaled the second longest in Dodgers history in the modern era (since 1900).

Ramos and Rafael Devers had two hits apiece for the Giants, who scored three or fewer runs for the 16th time in 24 games this season.

Freddie Freeman collected a pair of singles on a night without an extra-base hit for the Dodgers, who have lost four of six on a seven-game trip.

--Field Level Media